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. 2021 Jun 2;12:689132. doi: 10.3389/fimmu.2021.689132
AE Adverse event
ANG2 Angiopoietin-2
APC Antigen-presenting cell
CCL2 C-C motif chemokine ligand 2
CCL20 C-C motif chemokine ligand 20
CCL22 C-C motif chemokine ligand 22
CCL28 C-C motif chemokine ligand 28
CIK Cytokine-induced killer cell
CSF1 Colony stimulating factor 1
CTLA4 Cytotoxic T-lymphocyte-associated protein 4
CXCL12 C-X-C motif chemokine ligand 12
CXCR4 C-X-C motif chemokine receptor 4
DC Dendritic cell
EC Endothelial cell
EMA Exponential moving average
FDA Food and Drug Administration
FGFR Fibroblast growth factor receptor
GBM Glioblastoma multiforme
GM-CSF Granulocyte-macrophage colony stimulating factor
HCC Hepatocellular carcinoma
HIF-1α Hypoxia-inducible factor 1-alpha
HPV Human papillomavirus
ICAM1 Intercellular adhesion molecule 1
ICB Immune checkpoint blockade
ICI Immune checkpoint inhibitor
IDO Indoleamine 2,3-dioxygenase
IFN-γ Interferon-gamma
IL-10 Interleukin-10
IL-6 Interleukin-6
imDC Immature dendritic cell
Jak2/STAT3 Janus kinase 2/Signal transducer and activator of transcription 3
MDSC Myeloid-derived suppressive cell
MHC Major histocompatibility complex
NF-κB Nuclear factor κB
Nrp-1 Neuropilin 1
NSCLC Non-small cell lung cancer
ORR Objective response rate
OS Overall survival
PD-1 Programmed cell death-1
PDGFR Platelet-derived growth factor receptor
PD-L1 Programmed death ligand 1
PFS Progress-free survival
PGE2 Prostaglandin E2
PI3K Phosphoinositide-3-kinase
PIGF Placental growth factor
PLCγ Phospholipase C gamma
RTK Receptor tyrosine kinase
SDF-1α Stromal-cell-derived factor 1 alpha
TAM Tumor associated macrophage
TGF-β Transforming growth factor beta
TKI Tyrosine kinase inhibitor
TMB Tumor burden
TME Tumor microenvironment
TPS Tumor proportion score
Tregs Regulatory T cells
VCAM1 Vascular cell adhesion protein 1
VEGF Vascular endothelial growth factor
VEGFR Vascular endothelial growth factor receptor