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. 2021 Jun 16;21:580. doi: 10.1186/s12879-021-06257-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Per-individual LFA performance. Colors represent scores computed for IgG (top panel) and IgM (lower panel), where dark red = + 1 (operators all agree a band is present) and dark blue = −1 (operators all agree there is no band) with intermediate colors (pink and light blue) representing varying degrees of operator disagreement. Grey represents invalid runs. Samples are ordered within the COVID-, COVID-HIV+, and COVID+ groups in order of decreasing average score across all LFAs for both antibodies. Clinical variables include age (< 50 yrs.: light blue, 50-69 yrs.: intermediate blue, ≥70 yrs.: dark blue), sex (blue: male, pink: female), disease severity (hospitalized: light green, ICU: orange, ICU + respirator: red, deceased: black), and weeks post symptom-onset (dark green: 1–2 weeks, lightest green: ≥5 weeks)