TABLE 1.

Clinical parameters

Parameters Laboratory	Basal	ECCO2R				24 h post ECCO2R
		24 h	7 days	14 days	27 days
Hemoglobin (gr/L)	119	75	81	76	68	8,2
Leukocytes (109/L)	8.8	13.7	15.2	14.2	16.3	13870
Platelets (109/L)	398	321	176	166	393	408000
CRP (nmol/L)	722.8	761.9	1160	1583	393.3	310.4
Ureic nitrogen (mmol/L)	5.0	5.7	7.0	6.4	21.5	55
Creatinine (umol/L)	53.0	23.5	23.5	35.36	79.5	0.97
Sodium (mmol/L)	133.0	136.4	134.0	141.0	143.0	141
Potassium (mmol/L)	4.3	4.8	4.7	3.7	4.6	4.8
Ventilatories	​ ​ 3.0	​ ​ 2.5	​ ​ 2.5	​ ​ 3.0	​ ​ 4.0	​ ​ 4.0
Vt (ml/kg ideal)
RR (breaths/min)	60	24	26	24	30	30
PEEP (cmH2O)	4	4	4	4	4	4
Plateau pressure (cmH2O)	18	18	19	19	18	18
Distension pressure (cmH2O)	13	14	15	15	14	14
Compliance (ml/cmH2O)	16	16	15	15	16	16
PaO2/FiO2	81.4	157.4	178.2	207.1	233.0	234.2
Blood gases	​ ​ 7.21	​ ​ 7.37	​ ​ 7.37	​ ​ 7.40	​ ​ 7.40	​ ​ 7.39
pH
PaO2 (mmHg)	94.4	78,7	77.0	93.2	94.3	82.0
PaCO2 (mmHg)	96.8	54.4	50.7	49.4	42.0	45.0
Bicarbonate (mmol/L)	37.5	30.9	29.2	30.2	25.7	26.7
Lactate (mmol/L)	0.7	0.6	0.7	‐	‐	‐
ECCO2R	​ ​ 500	​ ​ 400	​ ​ 300	​ ​ 320	​ ​ 400	​ ​ ‐
Blood flow (ml/min)
Oxygen flow (L/min)	7	7	7	6	4	‐
CO2 removal (ml/min)	‐	‐	61	57	‐	‐
Hemodynamics	​ ​ 89	​ ​ 77	​ ​ 78	​ ​ 124	​ ​ 74	​ ​ 91
Mean arterial pressure (mmHg)
HR (heartbeat/min)	88	106	119	83	101	98
Norepinephrine dose (ug/kg/min)	0.01	0.10	0.00	0.00	0.00	0.00

Abbreviations: CRP, C‐reactive protein; ECCO₂R, extracorporeal CO₂ removal; FiO₂, inspired oxygen fraction; HR, heart rate; PaCO₂, partial pressure of carbon dioxide; PaO₂, partial pressure of oxygen; PEEP, positive end‐expiratory pressure; RR, respiratory rate; TV: tidal volume.

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