Figure 1. Selection of Trials for Inclusion in the Review and Meta-analysis.

NSAIDs indicates nonsteroidal anti-inflammatory drugs.

^aOther sources include reference mining of the included studies, gray literature search, and the technical experts panel.

^bThe purpose of using these systematic reviews and clinical trial registries was to identify relevant studies that may have been missed in the database search and in other sources. The studies found matched those that were already included, and no additional studies were identified through existing systematic reviews and clinical trial registries.