Table 1.
Initial Laboratory* and Microbiological Findings.
| Parameter | Patient’s value | Units | Reference value |
|---|---|---|---|
| Complete Blood Count | |||
| White blood cell count | 6.9 | 109/L | 4.5-13.0 |
| Hemoglobin | 10.6 | g/dL | 13.0-16.0 |
| MCV | 83.4 | fL | 78.0-98.0 |
| Platelet count | 183 | 109/L | 150-440 |
| Complete metabolic panel | |||
| Sodium | 143 | mmol/L | 135-145 |
| Potassium | 4.3 | mmol/L | 3.4-4.7 |
| Chloride | 105 | mmol/L | 98-107 |
| CO2 | 22.0 | mmol/L | 22.0-30.0 |
| BUN | 12 | mg/dL | 5-17 |
| Creatinine | 0.39 | mg/dL | 0.30-0.90 |
| Anion gap | 16 | mmol/L | 7-15 |
| Glucose | 128 | mg/dL | 70-179 |
| Calcium | 9.0 | mg/dL | 8.8-10.8 |
| Magnesium | 2.0 | mg/dL | 1.6-2.2 |
| Phosphorus | 3.9 | mg/dL | 4.0-5.7 |
| Albumin | 4.1 | g/dL | 3.5-5.0 |
| Total Protein | 7.9 | g/dL | 6.5-8.3 |
| Total Bilirubin | 0.2 | mg/dL | 0.0 -1.2 |
| AST | 53 | U/L | 10-40 |
| ALT | 37 | U/L | <50 |
| Alkaline Phosphatase | 132 | U/L | 130-560 |
| Cardiac Enzymes | |||
| Troponin I | <0.034 | ng/mL | <0.034 |
| Pro-BNP | 547.0 | pg/mL | 0.0-178.0 |
| ESR | 19.0 | mm/h | 0-20 |
| CRP | 19.1 | mg/L | <10.0 |
| LDH | 742 | U/L | 380-770 |
| Coagulation Panel | |||
| PT | 14.4 | sec | 10.2-13.1 |
| INR | 1.25 | N/A | N/A |
| APTT | 36.5 | sec | 25.9-39.5 |
| D-Dimer | 3,493 | DDU | <230 |
| Fibrinogen | 316 | mg/dL | 177-386 |
| Infectious Disease Test Results | |||
| SARS-CoV-2 PCR (nasopharyngeal) | Positive | N/A | Negative |
| SARS-CoV-2 PCR (CSF) | Negative | N/A | Negative |
| Blood culture | No growth | N/A | No growth |
| CSF culture | No growth | N/A | No growth |
| 4th generation HIV Ag/Ab | Negative | N/A | Negative |
| CMV PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| EBV PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| HHV-6 PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| HSV 1/2 PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| VZV PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| Enterovirus PCR (serum and CSF) | Undetectable | N/A | Undetectable |
| Arbovirus panel (CSF) | Negative | N/A | Negative |
| Parvovirus B-19 PCR (serum) | Undetectable | N/A | Undetectable |
| Bartonella antibody panel (serum) | Negative | N/A | Negative |
| LCMV PCR/antibody (serum and CSF) | Negative | N/A | Negative |
| Naegleria PCR (CSF) | Undetectable | N/A | Undetectable |
| Balamuthia PCR (CSF) | Undetectable | N/A | Undetectable |
| Acanthamoeba PCR (CSF) | Undetectable | N/A | Undetectable |
| Baylisascaris procyonis Ab (serum) | Negative | N/A | Negative |
| Postmortem Microbiological Results | |||
| Aerobic culture, left lung | Candida parapsilosis 1, Lactobacillus | N/A | No growth |
| Aerobic culture, right lung | No growth | N/A | No growth |
| Aerobic culture, brain tissue | <1+ Candida parapsilosis 2 | N/A | No growth |
| Aerobic/anaerobic culture, spleen | No growth | N/A | No growth |
| AFB smear/culture, left lung | No growth | N/A | No growth |
| AFB smear/culture, right lung | No growth | N/A | No growth |
| AFB smear/culture, brain tissue | No growth | N/A | No growth |
| Fungal culture, left lung | 4+ Candida parapsilosis 1 | N/A | No growth |
| Fungal culture, right lung | No growth | N/A | No growth |
| Fungal culture, brain tissue | No growth | N/A | No growth |
| Respiratory pathogen panel, left lung | Negative | N/A | Negative |
| Respiratory pathogen panel, right lung | Negative | N/A | Negative |
| SARS-CoV-2 PCR (blood) | Negative | N/A | Negative |
| SARS-CoV-2 PCR (brain tissue) | Negative | N/A | Negative |
| SARS-CoV-2 PCR (left lung) | Negative | N/A | Negative |
| SARS-CoV-2 PCR (right lung) | Negative | N/A | Negative |
* Initial laboratory findings obtained while patient was in the emergency department.
1This fungal growth was likely related to the patient’s known aspiration event.
2Growth from aerobic culture of brain tissue was believed to be contamination from lung tissue at time of autopsy; growth in only 1 of 2 aerobic cultures from brain tissue.