Table 3.

Estimated adjusted effects of variables on mean femoral neck BMD at baseline and BMD change over 4.3 years follow-up (n = 753 patients, 1166 visits)

Variable	Estimated effect	95% CI	P value
Mean difference of BMD at baseline
Age at baseline (y)	-0.0037	-0.0044to-0.0029	< 0.0001
Gender
Men	Ref.		< 0.0001
Premenopausal women at baseline	-0.0481	-0.0833to-0.0130
Postmenopausal women	-0.0849	-0.1082to-0.0617
BMI at baseline (kg/m2)
<25	Ref.		< 0.0001
≥25	0.0894	0.0703to0.1086
Ethnicity
No African origin	Ref.		< 0.0001
African origin	0.0746	0.0486to0.1008
Tobacco use at baseline
Never smoking	Ref.		0.060
Former smoker	-0.0036	-0.0254 to 0.0179
Current smoker	-0.0341	-0.0626to-0.0059
CKD stages at baseline
1-2	Ref.		< 0.01
3a	-0.0171	-0.0458 to 0.0113
3b	-0.0313	-0.0598to-0.0030
4-5	-0.0575	-0.0894to-0.0257
log(PTH) at baseline	-0.0230	-0.0391to-0.0069	< 0.01
Mean BMD change
Time (yrs)	-0.0023	-0.0127 to 0.0082	0.677
BMI at baseline (kg/m2)
<25	Ref.		<0.05
≥25	0.0031	0.0002to0.0060
CKD stages at baseline
1-2	Ref.		0.099
3a	-0.0014	-0.0066 to 0.0037
3b	-0.0045	-0.0096 to 0.0005
4-5	-0.0004	-0.0060 to 0.0052
log(PTH) at baseline	-0.0005	-0.0032 to 0.0022	0.704

BMD, bone mineral density; BMI, body mass index; CI, confidence interval; CKD, chronic kidney disease; PTH: parathyroid hormone.

The factor center has been included as random effect