Table 4.

Estimated adjusted effects of variables on mean radius BMD at baseline and BMD change over 4.3 years follow-up (n = 753 patients, 1166 visits)

Variable	Estimated effect	95% CI	P value
Mean difference of BMD at baseline
Age at baseline (y)	-0.0017	-0.0023to-0.0012	< 0.0001
Gender
Men	Ref.		< 0.0001
Premenopausal women at baseline	-0.0941	-0.1216to-0.0666
Postmenopausal women	-0.1277	-0.1459to-0.1095
BMI at baseline (kg/m2)
<25	Ref.		< 0.001
≥25	0.0270	0.0119to0.0422
Ethnicity
No African origin	Ref.		0.204
African origin	0.0134	-0.0071 to 0.0339
Tobacco use at baseline
Never smoking	Ref.		0.088
Former smoker	-0.0184	-0.0353to-0.0014
Current smoker	-0.0002	-0.0224 to 0.0220
CKD stages at baseline
1-2	Ref.		0.467
3a	0.0171	-0.0056 to 0.0397
3b	0.0053	-0.0173 to 0.0279
4-5	0.0059	-0.0194 to 0.0311
log(PTH) at baseline	-0.0107	-0.0234 to 0.0021	0.105
Mean BMD change
Time (y)	-0.0158	-0.0292to-0.0023	<0.05
BMI at baseline (kg/m2)
<25	Ref.		0.545
≥25	-0.0011	-0.0048 to 0.0025
CKD stages at baseline
1-2	Ref.		0.951
3a	0.0012	-0.0054 to 0.0078
3b	0.0007	-0.0058 to 0.0073
4-5	-0.0002	-0.0075 to 0.0070
log(PTH) at baseline	0.0030	-0.0004 to 0.0065	0.089

BMD, bone mineral density; BMI, body mass index; CI, confidence interval; CKD, chronic kidney disease; PTH, parathyroid hormone.

The factor center has been included as random effect.