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. 2021 Apr 8;37(3):481–534. doi: 10.1002/joa3.12449
Recommendations for genetic evaluation of SCA survivors
COR LOE Recommendations References
1 B‐NR 1. Genetic evaluation of SCA survivors is recommended for those with a diagnosed or suspected genetic cardiac disease phenotype when the results are likely to influence diagnosis, management, or family screening. 84, 322
1 B‐NR 2. When genetic evaluation is performed in an SCA survivor with a suspected or diagnosed genetic cardiac disease phenotype, it is recommended that evaluations include only genes where there is robust gene–disease association. 84, 308
2b B‐NR 3. When genetic evaluation is performed in an SCA survivor with a suspected or diagnosed genetic cardiac disease phenotype, assessment of genes or genomic regions that are not known to be causally related may be considered in select circumstances. 84
2b B‐NR 4. Genetic evaluation of SCA survivors without a distinct genetic cardiac disease phenotype may be considered in select circumstances. 82, 330
3: No Benefit C‐EO 5. Genetic testing in SCA survivors with a well‐established nongenetic cause of SCA is not recommended.