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. 2021 Jun 16;43:24. doi: 10.1186/s41021-021-00199-x

Table 2.

Levels of Measured Endogenous Etheno DNA Adducts (see also [61])

DNA Source Adducts/108 nucleotides Method Reference
1,N6-ε-dAdo 3,N4-ε-dCyd 1,N2-ε-dGuo N2,3-ε-dGuo
Rat Liver 0.10–0.12 0.10–0.12 Immunoaffinity/32P labeling [47]
Liver 18–23 GC/MS [47]
Liver 120 560 HPLC/32P labeling [62]
Liver 0.011–0.012 0.016–0.017 Immunoaffinity/32P labeling [63]
Lung 0.4–0.5 1.8–3.8 Immunoaffinity/32P labeling [63]
Kidney 0.7–0.8 2.1–2.8 Immunoaffinity/32P labeling [63]
Lymphocytes 1.1 1.2 Immunoaffinity/32P labeling [63]
Hepatocytes 1.4 Immunoaffinity/GC/MS [64]
Hepatocytes NDa Immunoaffinity/GC/MS [65]
Human Hepatocytes 2.0 LC/MS [66]
Oral cells 0.77 0.61 LC/MS [67]
Placenta 74–84 LC/MS [68]
Placenta 1.1 LC/MS [69]
Pancreas 1.8 1.2 Immunoaffinity/32P labeling [70]

aND Not detected (< 4)