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. 2021 Jun 16;22:452. doi: 10.1186/s12864-021-07747-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Upstream regulators for DEGs in bovine CL from day 18 P and NP cows. Bar graphs show the top activated and inhibited upstream regulators in day 18 P cows compared to NP cows predicted by IPA analysis (default cut off Z-score > 2 or < − 2 and padj < 0.05). Green bars indicate the activated upstream regulators and the red bars indicate the upstream-inhibited regulators. The x-axis represents the Z-score