Fig. 2.

Effect of cordycepin on microglia/macrophage polarization. a Representative CD16/Iba1 and CD206/Iba1 stained images of cortex (CTX) and striatum (STR) on 3 days and 7 days after TBI. White arrows indicate double-positive cells. Scale bar: 20 μm. b, c Quantification of the numbers of CD16⁺Iba1⁺cells (b)and CD206⁺Iba1⁺cells (c) in CTX and STR. d, e qPCR results of pro-inflammatory (d) and anti-inflammatory markers (e) on 7 days after TBI. n=3-7/group. ^##p < 0.01 and ^###p < 0.001; or *p < 0.05, **p < 0.01, and ***p < 0.001 as indicated