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. 2021 Jun 15;18:137. doi: 10.1186/s12974-021-02188-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Effect of cordycepin on peripheral immune cell infiltration. a Illustration of flow cytometry analysis of circulating immune cells in the brain on 3 days after TBI. b Quantification of the numbers of infiltrating immune cells to the brain. n=5/group. c 3D-reconstructed image of confocal pictures of Ly6G/tomato-lectin straining. Scale bar: 20 μm. d Representative images of Ly6G straining. White arrows indicate Ly6G+cells. Scale bar: 20 μm. e Quantification of numbers of total Ly6G+cells and Ly6G+cells in CTX and STR, n=6/group. And correlation analysis of Ly6G+cells and CD16+Iba1+cells. n=5/group. ^#p < 0.05, ^###p < 0.001, or *p < 0.05 as indicated