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. 2021 Jun 15;19:184. doi: 10.1186/s12951-021-00931-3

Table 1.

IC50 values of MTX formulations in JEG-3 cells and Pricell-0051 cells

IC50
(μg/mL)
JEG-3 Pricell-0051
free MTX MTX + Cy-lipid Lipo@MTX Cy-Lipo@MTX free MTX MTX + Cy-lipid Lipo@MTX Cy-Lipo@MTX
Mean 19.55* 5.57 12.84* 1.51 32.18* 13.81 25.67 4.08
SD 1.73 1.92 4.90 0.88 6.84 9.27 17.57 2.56

*P < 0.05, vs Cy-Lipo@MTX group