Table 3.
Toxicity outcomes in the mistletoe and non-mistletoe groups
| Toxicity | CTCAE | P-value¶ | |||||||
|---|---|---|---|---|---|---|---|---|---|
| MG (n = 15) | NMG (n = 37) | ||||||||
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | ||
| Neutropenia | 0 | 0 | 0 | 0 | 0 | 1 (2.7) | 0 | 0 | > 0.99 |
| Anemia | 0 | 0 | 0 | 0 | 0 | 0 | 1 (2.7) | 0 | > 0.99 |
| Thrombocytopenia | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – |
| Nausea | 4 (26.7) | 0 | 0 | 0 | 6 (16.2) | 0 | 0 | 0 | 0.448 |
| Vomiting | 1 (6.7) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.288 |
| Diarrhea | 2 (13.3) | 0 | 0 | 0 | 5 (13.5) | 0 | 0 | 0 | > 0.99 |
| Constipation | 0 | 0 | 0 | 0 | 4 (2.8) | 0 | 0 | 0 | 0.311 |
| Proctitis | 9 (60.0) | 0 | 0 | 0 | 10 (27.0) | 0 | 0 | 0 | 0.054 |
| Oral mucositis | 0 | 0 | 0 | 0 | 1 (2.7) | 0 | 0 | 0 | > 0.99 |
| Peripheral neuropathy | 1 (6.7) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.288 |
| Pruritus | 3 (20.0) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.021 |
Data are presented as n (%)
¶Chi-square test or Fisher’s exact test
CTCAE, Common Terminology Criteria for Adverse Events version 3.0; MG, mistletoe group; NMG, non-mistletoe group