Table 4.
CONTROLS | ADENOCARCINOMA (1) | SQUAMOUS CELL CARCINOMA (2) | SMALL CELL CARCINOMA (3) | p-value for Homogeneity Test | ||||||
---|---|---|---|---|---|---|---|---|---|---|
N = 757 | N = 514 | OR (95%CI) | N = 67 | OR (95%CI) | N = 88 | OR (95%CI) | (1)/(2) | (1)/(3) | (2)/(3) | |
SMOKING STATUS | ||||||||||
Never smokers | 341 | 129 | Ref | 7 | Ref | 3 | Ref | |||
Former smokers | 246 | 149 | 1.76 (1.31; 2.37) | 24 | 5.23 (2.17; 12.59) | 15 | 7.66 (2.17; 27.10) | 0.15 | 0.89 | 0.43 |
Current smokers | 170 | 236 | 3.50 (2.61; 4.70) | 36 | 12.56 (5.33; 29.58) | 70 | 59.43 (18.11; 194.97) | 0.01 | < 0.001 | 0.01 |
INTENSITY | ||||||||||
Per 10 cigarettes/day | 2.04 (1.79; 2.31) | 2.82 (2.23; 3.56) | 3.45 (2.79; 4.28) | 0.01 | < 0.001 | 0.14 | ||||
DURATION | ||||||||||
Per 10 years | 1.44 (1.35; 1.54) | 2.04 (1.71; 2.43) | 2.83 (2.26; 3.55) | < 0.001 | < 0.001 | 0.02 | ||||
PACK-YEARS | ||||||||||
Per 10 pack-years | 1.55 (1.45; 1.66) | 1.86 (1.66; 2.09) | 2.13 (1.90; 2.38) | < 0.001 | < 0.001 | 0.04 | ||||
TIME SINCE CESSATION (among ever smokers) | ||||||||||
Per 1 year | 0.96 (0.94; 0.97) | 0.92 (0.89; 0.95) | 0.87 (0.82; 0.91) | 0.03 | < 0.001 | 0.05 | ||||
CSI | ||||||||||
Per 1 CSI unit | 2.54 (2.18; 2.96) | 5.12 (3.61; 7.26) | 9.98 (6.60; 15.09) | < 0.001 | < 0.001 | 0.01 |
Abbreviations: CI confidence interval, CSI comprehensive smoking index, OR odds ratio
Odds ratio were adjusted for age (continuous), area of residence, education, and BMI 2 years before the interview (continuous)