Table 1.
Demographic and clinical data of patients from the CRD and NCRD populations.
| NCRD population (n=2155) | CRD population (n=384) | p-value | |
|---|---|---|---|
| Demographic variables | |||
| Age, years (mean ± SD) | 61.1 ± 19.3 | 71.4 ± 14.8 | **** |
| Female (%) | 1100 (51.0) | 164 (42.7) | **** |
| BMI (mean ± SD) | 27.0 ± 5.1 | 30.6 ± 26.2 | *** |
| Smoking status (%) | |||
| Never | 1675 (77.7) | 217 (56.5) | **** |
| Former smoker | 356 (16.5) | 137 (35.7) | **** |
| Smoker | 124 (5.8) | 30 (7.8) | N.S. |
| Hospitalization parameters | |||
| Fatal outcome (%) | 234 (10.8) | 86 (22.4) | **** |
| ICU (%) | 125 (5.8) | 24 (6.2) | N.S. |
| First SpO2 (%) | 94.0 (92.0-96.0) | 94.0 (91.0-96.0) | N.S. |
| Inflammatory pattern | |||
| Eosinophils (×109/L) | 0.07 (0.01-0.18) | 0.11 (0.02-0.21) | ** |
| Eosinopenia (%) | 373 (17.3) | 73 (19.0) | N.S. |
| Leukocytes (×109/L) | 7.45 (5.14-10.27) | 6.90 (5.46-8.80) | N.S. |
| Lymphocytes (× 109/L) | 1.40 (0.9-2.00) | 1.60 (0.90-2.30) | N.S. |
| Basophils (×1010/L) | 0.34 ± 0.5 | 0.43 ± 0.5 | * |
| Neutrophils (× 109/L) | 4.10 (3.10-6.00) | 4.40 (3.05-5.80) | N.S. |
| Monocytes (×109/L) | 0.50 (0.30-0.60) | 0.50 (0.40-0.70) | N.S. |
| Laboratory Parameters | |||
| D-dimer (μg/mL) | 0.52 (0.29-0.97) | 0.48 (0.27-1.09) | N.S. |
| Ferritin (μg/mL) | 606 (254–1609) | 156 (69.7-357.0) | **** |
| C-reactive protein (μg/mL) | 4.11 (1.10-8.99) | 2.80 (0.83-8.43) | N.S. |
| Comorbidities | |||
| Heart disease (%) | 371 (17.22) | 162 (42.19) | **** |
| Diabetes mellitus (%) | 317 (14.71) | 86 (22.40) | *** |
| Renal disease (%) | 141 (6.54) | 58 (15.10) | **** |
| Neurological disease (%) | 214 (9.93) | 70 (18.23) | **** |
| Cancer (%) | 108 (5.01) | 38 (9.89) | *** |
| High blood pressure (%) | 837 (38.84) | 217 (56.51) | **** |
CRD, chronic respiratory disease group; NCRD, non-chronic respiratory disease group; BMI, body mass index; ICU, intensive care unit; N.S., no statistically significant difference found. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.