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. 2021 Mar 15;162(7):2070–2086. doi: 10.1097/j.pain.0000000000002207

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Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 6. — Localization of Anxa1 in L4 ipsilateral DRG. (A) Under Sham conditions, Anxa1 is colocalized with GFAP-positive cells (ie, satellite glia cells) but not with neuronal subpopulations (labeled by indicated marker proteins) or retrogradely labeled neurons (True Blue positive) in ipsilateral L4 DRG. (B) By contrast, plantar incision (postoperative day 1) induced neuronal expression of Anxa1 in Peripherin-, CGRP- and IB4-positive neurons (indicated by arrows, Inset). Retrogradely labeled neurons are marked with an asterisk (Inset). Scale bar = 50 µm (composite), 20 µm (Inset). DRG, dorsal root ganglia.