Table 2.

Dosage regimen of different Wister rat groups used in vivo assessment.

Group number	Dosage regimen
Gp 1: Placebo (control)	Saline (2 ml/kg) intraperitoneally (i.p.) once then administered orally saline at dose of 5 ml/kg daily
Gp 2:MERS infected (untreated)	Intranasally infected with 105 pfu/50 μl of virus
Gp 3: Piperine suspension-treated GP	After infection an oral dose of 50 mg/kg (Selvendiran et al., 2006) once a day for 6 days
Gp 4: Piperine bilosome-treated GP	After infection an oral dose of 50 mg/kg (Selvendiran et al., 2006) once a day for 6 days