Table 4.
32.21 Output factorial analysis data of piperine-loaded bilosomal formulae and the predicted and observed responses of the optimum formula (F2).
| Responses | EE (%) | Particle size (nm) | Q8hr (%) |
|---|---|---|---|
| R 2 | 0.9996 | 0.9938 | 0.9581 |
| Adjusted R2 | 0.9983 | 0.9737 | 0.8219 |
| Predicted R2 | 0.9917 | 0.8745 | 0.1513 |
| Adequate precision | 94.986 | 21.355 | 9.52 |
| Significant factors | X1, X2, X3 | X1, X2, X3 | X1, X2 |
| Observed value of the optimal formula (F2) | 97.2 | 220.2 | 88.2 |
| Predicted value of the optimal formula (F2) | 96.89 | 216 | 88.6 |
EE%: entrapment efficiency percentage; Q8hr: % of piperine released after 8 h.