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. 2021 May 31;10(5):1814–1817. doi: 10.4103/jfmpc.jfmpc_2108_20

Table 2.

Literature review

Study Date Conclusion of the study
Fang et al.[17] February 2020 In a series of 51 patients with chest CT and RT-PCR assay performed within 3 days, the sensitivity of CT for COVID-19 infection was 98% compared to RT-PCR sensitivity of 71% (p<0.001)
Feng et al.[21] April 2020 Chest CT is more sensitive than RT-PCR to detect early change of COVID-19 in cases which RT-PCR tests show negative results. In this case, fifth RT-PCR test was positive with initial positive CT and subsequent four negative RT-PCR tests.
Long C, et al.[4] May 2020 RT-PCR may produce initial false negative results. The authors suggest that patients with typical CT findings but negative RT-PCR results should be isolated, and RT-PCR should be repeated to avoid misdiagnosis
Ai T, et al.[19] August 2020 The positive rates of RT-PCR assay and chest CT imaging in study cohort were 59% and 88% respectively.
With RT-PCR as a reference, the sensitivity of chest CT imaging for COVID-19 was 97%.
With analysis of serial RT-PCR assays and CT scans, 60% to 93% of patients had initial positive chest CT consistent with COVID-19 before the initial positive RT-PCR results.
Xie X, et al.[22] August 2020 A combination of repeated swab tests and CT scanning may be helpful when for individuals with high clinical suspicion of nCoV infection but negative RT-PCR screening