Fig. 5. (a) An illustration of rec-CF5/CR5 treated with SN21-LK15. (b) Confocal microscopy images of HeLa cells treated with rec-CF5/CR5/SN21-LK15 (CF: green, CR: red). (c) Time lapse images (30–70 min) of CF (green) and CR (magenta) for the boxed area in (b). (d and e) Time-course changes of (d) the fluorescence emission intensity and (e) the ratio (CF/CR = 518/582) for macropinosome shown in (c).