. 2021 Jun 4;21(8):1–188.

Table 9:

Quality of Life Score After Mechanochemical Ablation vs. Radiofrequency Ablation

	Baseline Score, Median (IQR)			Follow-Up Score, Median (IQR)
Author, Year (Study Design)	MOCA	RFA	Follow-Up Time Point	MOCA	RFA	P Value
Disease-Specific Quality of Life: AVVQ
Holewijn et al, 2019⁷⁹ (RCT)	14.3 (2.75–31.25)^a	13.31 (3.16–29.72)^a	4 wk 1 y 2 y	8.9 (2.12–19.85)^a 7.5 (2.05–16.93)^a 5 (3.23–17.90)^a	7.6 (2.19–17.20)^a 7.0 (2.4–16.44)^a 4.8 (3.44–16.02)^a	.223 .753 .573
Lane et al, 2017; Bootun et al, 2016^73,74(RCT)	18.89^b (NR)	19.55^b (NR)	1 mo 6 mo	12.1^b (7.3–21.2)^b 11.8^b (7.2–20.5)^b	12.9^b (6.6–20.4)^b 9.4^b (3.6–21.4)^b	.799 .511
Van Eekeren et al, 2013⁷⁵ (prospective comparative cohort)	7.1 (5.3–9.2)	9.5 (4.5–16.4)	6 wk	5.0 (3–8.5)	4.5 (1.5–11.2)	.17
Generic Quality of Life: EQ-5D
Lane et al, 2017; Bootun et al, 2016^73,74 (RCT)	.761 (NR)^c	.730 (NR)^c	1 mo 6 mo	.761 (0.659–1) .761 (.690–1)	.761 (.690–1) .761 (.486–1)	.939 .125
Generic Quality of Life: EQ-5D VAS
Lane et al, 2017; Bootun et al, 2016^73,74 (RCT)	80.0 (NR)	84.5 (NR)	1 mo 6 mo	85 (60–95)^d 85 (60–93)^d	87 (80–90)^d 89 (70–95)^d	.227 .302

Abbreviations: AVVQ, Aberdeen Varicose Vein Questionnaire; EQ-5D, EuroQol 5-Dimensions questionnaire; EVLA, endovenous laser ablation; IQR, interquartile range; mo, month(s); MOCA, mechanochemical ablation; NR, not reported; NS, not significant; RCT, randomized controlled trial; RFA, radiofrequency ablation; VAS, visual analogue scale; wk, week(s); y, year.

Estimated from Figure 4 in Holewijn et al⁷⁹ using WebPlotDigitizer software.⁴³

Scores presumed to be medians and interquartile ranges as per Table 1 and boxplot in Figure 4 of Lane et al.⁷⁴ Baseline and 1-month follow-up also reported as mean score and standard deviation in Table 3 of earlier publication by Bootun et al⁷³ with no differences between groups at baseline or follow-up (P > .05).

Between-group difference at baseline was not significant (P = .989).

Scores in parentheses presumed to reflect IQR based on article stating that data are reported as medians.⁷⁴