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. 2021 Jun 2;12:677596. doi: 10.3389/fmicb.2021.677596

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Copyright © 2021 Mao, Yuan, Yang, Liu, Cheng, Luo, Liu, Yao, Sun, Cai and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Methanol assimilation pathways. The natural pathways (A) and artificial pathways without non-natural reactions (B) or artificial pathways based on non-natural reactions (C). R5P, D-ribose 5-phosphate; Ru5P, D-ribulose 5-phosphate; Xu5P, D-xylulose 5-phosphate; DHA, dihydroxyacetone; G3P, D-glyceraldehyde 3-phosphate; F6P, D-fructose 6-phosphate; FBP, fructose 1,6-bisphosphate; E4P, D-erythrose 4-phosphate; H6P, D-hexulose 6-phosphate; S7P, D-sedoheptulose 7-phosphate; SBP, D-sedoheptulose 1,7-bisphosphate; DHAP, dihydroxyacetone phosphate; PEP, phosphoenolpyruvate; PYR, pyruvate; RuBP, D-ribulose 1,5-bisphosphate; 3PG, D-glycerate 3-phosphosphate; 13dPG, 3-phospho-D-glyceroyl phosphate; OAA, oxaloacetate; GALD, glycolaldehyde; Ara5P, D-arabinose 5-phosphate; PGA, D-glycerate 2-phosphate; AcP, acetyl-phosphate; and AcCoA, acetyl-coenzyme A.