FIG 5.

Mouse serum antibody adherence inhibition assays show similar levels of in vitro protection by MecVax- or CFA/I/II/IV MEFA-induced antibodies against adherence of CFA/I and CS1 to CS6 adhesins. Percentages of ETEC or E. coli bacteria (CFU) expressing CFA/I, CS1, CS2, CS3, CS4/CS6, CS5/CS6, or CS6 that were adherent to Caco-2 cells were compared after incubation with serum samples from three groups of mice: i.m. immunized with MecVax (white bars), with CFA/I/II/IV MEFA protein (gray bars), or with PBS (black bars) as the control. Bars represent the mean percentages of adherent bacterial CFU, and error bars the standard deviations. *, P < 0.05.