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. 2021 Jun 4;17(6):e1009534. doi: 10.1371/journal.pgen.1009534

Table 1. Examples of possible proportional genotype risk underlying genetic loci.

Biological Action Homozygous Referent
AA
Heterozygous
Aa
Homozygous Alternate
aa
Recessive (REC) 0% 0% 100%
Sub-Additive (SUB) 0% 25% 100%
Additive (ADD) 0% 50% 100%
Super-Additive (SUP) 0% 75% 100%
Dominant (DOM) 0% 100% 100%