Differences in selected dose-volume metrics between the three methods of synthetic CT (sCT) and CT. AD,DS,DSL denotes planning on CT and re-calculating on the sCTD,DS,DSL images (Plan 1). BD,DS,DSL codifies planning on the sCTD,DS,DSL images and re-calculating on CT (Plan 2). Coloured circles encode patient number (red, blue, green, orange, yellow and brown codify patients 1 to 6, respectively). Black diamonds show the results of re-planning patient 2 (blue) with rescaled lung HUs. Black crosses show significant differences between sCT and CT; brackets and stars label significant absolute differences between sCT methods. Mandatory clinical goals for the five patients planned with 55 Gy in 5 fractions are listed on the top left-hand side of each subplot.