Table 1B.
Clinical features of GBS infections in infants from multiple births (German/Swiss cohort).
| Birth | GBS LOS episode | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient ID1 | gestational age (w) | zygocity/chorionicity | Sex | birth weight (g) | Chorioamnionitis | Delivery mode | GBS maternal swab | ATX labour/birth | indication for ATX | ATX before LOS (d) | age at LOS onset (d) | onset at HM/HS | Signs and symptoms | GBS detection | breastfeeding/GBS in breast milk | infant skin/mucosal swabs | Serotype | Sequence type | ATX (d) | outcome | ATB mother | continuation of breastfeeding | recurrence | |
| LOS - all children affected | 36a | 31 | N/A | F | 1820 | N | CS | N | Y | Sc | 4 | 28 | HS | S | B | Y/NA | neg | N/A | N/A | 10 | G | N | N | N |
| 36b | 31 | N/A | F | 1440 | N | CS | N | Y | SC | 0 | 16 | HS | M | B/CSF | Y/NA | neg | N/A | N/A | 16 | NS | N | N | N | |
| 37a | 26 | DZ | M | 890 | Y | CS | N/A | Y | PR | 2 | 84 | HM | AA | B | N/- | N/A | N/A | N/A | N/A | L/C | N | F | N | |
| 37b | 26 | DZ | F | 810 | Y | CS | N/A | Y | PR | 2 | 84 | HM | S | – | N/- | pos | N/A | N/A | 5 | N/A | N | F | Y | |
| 38a | 28 | DZ | M | 1125 | N | CS | N | Y | PR | 3 | 48 | HS | Cl | B/CSF | Y/neg | neg | III | 17 | 19 | G | N | Y | Y | |
| 38b | 28 | DZ | M | 1190 | N | CS | N | Y | PR | 3 | 48 | HS | Cl | B | Y/neg | neg | III | 17 | 19 | G | N | Y | N | |
| 39a | 26 | DZ | M | 800 | Y | CS | N | Y | PR | 24 | 117 | HM | S | B | Y/neg | neg | V | N/A | 14 | G | R | N | N | |
| 39b | 26 | DZ | M | 850 | Y | CS | N | Y | PR | 8 | 112 | HM | M | B/CSF | Y/neg | pos | V | N/A | 21 | G | R | N | N | |
| 39c | 26 | DZ | M | 890 | Y | CS | N | Y | PR | 20 | 118 | HM | S | B | Y/neg | neg | V | N/A | 14 | G | R | N | N | |
| 40a | 32 | DC | F | 1730 | N | CS | N | Y | PR | 0 | 35 | HS | S | B | Y/pos | N/A | N/A | N/A | 14 | G | Y | N | Y | |
| 64 | HM | S | B | N/- | N/A | N/A | N/A | 14 | G | N | F | – | ||||||||||||
| 40b | 32 | DC | F | 1470 | N | CS | N | Y | PR | 0 | 28 | HS | M | B/CSF | Y/pos | N/A | N/A | N/A | 21 | G | Y | N | Y | |
| 63 | HM | M | B | N/- | N/A | N/A | N/A | 14 | G | N | F | – | ||||||||||||
| 41a | 25 | DC | M | 950 | N | N/A | N | Y | N/A | 5 | 14 | HS | S | B | Y/pos | pos | N/A | N/A | 14 | G | N | Y * | N | |
| 41b | 25 | DC | M | 875 | N | N/A | N | Y | N/A | 10 | 20 | HS | M | B/CSF | Y/pos | pos | N/A | N/A | 21 | NS | N | Y * | N | |
| 42a | 32 | M | F | 1600 | N | CS | N | N | – | 0 | 69 | HM | S | B | Y/neg | neg | N/A | N/A | 16 | G | N | Y | N | |
| 42b | 32 | M | F | 1190 | N | CS | N | N | – | 0 | 51 | HM | S | B | Y/neg | neg | N/A | N/A | 16 | G | N | Y | N | |
| 42c | 32 | M | F | 1250 | N | CS | N | N | – | 0 | 58 | HM | S | B | Y/neg | neg | N/A | N/A | 16 | G | N | Y | N | |
| 43a | 36 | N/A | M | 2350 | N | V | N/A | N | – | N/A | 11 | N/A | N/A | B | N/A | N/A | III | N/A | 10 | G | N/A | N/A | N/A | |
| 43b | 36 | N/A | M | 2160 | N | V | N/A | N | – | N/A | 11 | N/A | N/A | B | N/A | N/A | III | N/A | 14 | G | N/A | N/A | N/A | |
| 44a | 32 | DZ | F | 1600 | N | CS | N | Y | Sc | N/A | N/A | N/A | N/A | B | Y/pos | N/A | N/A | N/A | N/A | G | N/A | N/A | N/A | |
| 44b | 32 | DZ | M | 1860 | N | CS | N | Y | Sc | N/A | N/A | N/A | N/A | B | Y/pos | N/A | N/A | N/A | N/A | G | N/A | N/A | N/A | |
AA, acute abdomen; ATX, antibiotics; B, Blood; Cl, cellulitis; CS, caesarean section; CSF, cerebrospinal fluid; DC, dichorionic; DZ, dizygotic; G, good; HM, home; HS, hospital; L/C, laparotomy+colostoma; Me, meningitis; N/A, not available; NS, neurologic sequelae; PR, PROM; R, recommended; SP, Section Prophylaxis; S, sepsis; V, vaginal delivery *sterilization.
1Infants from the same family are indicated with the same number plus a,b,c.