Table 1.
Association of genotypic resistance (presence of at least one resistance marker to one drug) with lineages and geographical region
South Africa was not included because it includes one genome. * indicates reference category.
|
Lineage/region |
No. (%) with DR (total N=87) |
No. (%) with no DR (total N=580) |
Univariate regression |
Multivariate regression |
||
|---|---|---|---|---|---|---|
|
OR (95 % CI) |
P value |
OR (95 % CI) |
P value |
|||
|
Lineage |
||||||
|
L6* |
31 (35.6) |
287 (49.5) |
– |
– |
– |
– |
|
L5 |
56 (64.4) |
293 (50.5) |
1.76 (1.08–2.92) |
0.0168 |
0.85 (0.48–1.50) |
0.589 |
|
Region |
||||||
|
WWest Africa* |
34 (39.1) |
465 (80.2) |
– |
– |
– |
– |
|
Central Africa |
7 (8.0) |
49 (8.4) |
1.95 (0.82–4.64) |
0.129 |
2.11 (0.84–5.26) |
0.108 |
|
EWest Africa |
37 (42.5) |
44 (7.6) |
11.50 (6.57–20.11) |
<0.01 |
12.35 (6.64–22.97) |
<0.01 |
|
Non-African |
9 (10.3) |
22 (3.8) |
5.59 (2.39–13.09) |
<0.01 |
5.74 (2.43–13.52) |
<0.01 |
DR, Drug resistance marker.