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. 2020 Nov 27;7(2):000481. doi: 10.1099/mgen.0.000481

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© 2021 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License.

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Fig. 3. — Heatmap distribution and occurrence of the genetic determinants involved in AMR by high-level (a) and low-level (b) WGS-based genogroups. Genetic determinants are ordered by the affected antimicrobial drug class/antibiotic, with resistance or decreased susceptibility effect described at the bottom. Heatmap colour range correlates with the percentage of isolates carrying each genetic determinant within a given WGS-based genogroup. The numbers of isolates within each genogroup are presented on the right of each panel. The contextual neighbour-joining phylogenetic tree at the left side of each panel was generated based on the MScgMLST allelic profiles using GrapeTree v1.5.0 software [56]. The asterisk indicates that the combination of these three mutations has been proposed as potentially inducing resistance to cephalosporins [8]. AZM, Azithromycin; CFM, cefixime; CIP, ciprofloxacin; CRO, ceftriaxone; PEN, penicillins; RI, rifampicin; SPT, spectinomycin, SUL, sulphonamides; TET, tetracycline.