Figure 1.
NLRP3 inflammasome correlates with increased body weight in patients. (A) Quantification of BMI in non-obese control (Ctl) and obese (Ob) patients. Representative western blots and quantification of NLRP3 (B) and ASC (C) in atrial tissues of patients. Representative western blots (D) and quantification of pro-caspase-1 (Pro-Casp1, E), and active caspase-1 (p20, F) in atrial tissues of patients. Representative western blots (G) and quantification of pro-IL-1β (H), and mature IL-1β (I) in atrial tissues of patients. *P < 0.05, **P < 0.01 using Student’s t-test.