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. 2021 Jun 10;184(12):3281–3298.e22. doi: 10.1016/j.cell.2021.04.028

Figure 2.

Figure 2

Epithelial cell heterogeneity and stem cell differences across organs

(A–D) Epithelial cell UMAP, colored by cell type in the developing human (A) lung, (B) esophagus, (C) stomach, and (D) intestine.

(E) Epithelial stem cell UMAP from multiple organs, with cells colored by tissue. The inset shows feature plots of LGR5 and OLFM4 expression.

(F) Heatmap showing expression patterns of TFs across epithelial stem cell bins ordered by pseudospace. The top sidebar shows the tissue proportion within each cell bin (20 cells/bin).