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. Author manuscript; available in PMC: 2021 Jun 16.
Published in final edited form as: Respir Physiol Neurobiol. 2020 Apr 5;277:103438. doi: 10.1016/j.resp.2020.103438

Fig. 1.

Fig. 1.

Pharmacokinetic profile of the two doses of AF-454 used in this study as detected in the plasma and brain from newborn rats at the day of birth (P0). Gray symbols, 5 mg/kg at 10 min (n = 5), 20 min (n = 5) and 60 min (n = 4); Black symbols, 10 mg/kg at 10 min (n = 5), 20 min (n = 7) and 60 min (n = 8). Data were analysed by two-way ANOVA with Tukey post hoc test. *P < 0.05 vs 5 mg/kg at the same time point.