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. 2021 Jun 2;11:684396. doi: 10.3389/fonc.2021.684396

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Copyright © 2021 Simonetti, Angeli, Petracci, Fonzi, Vedovato, Sperotto, Padella, Ghetti, Ferrari, Robustelli, Di Liddo, Conconi, Papayannidis, Cerchione, Rondoni, Astolfi, Ottaviani, Martinelli and Gottardi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ADM expression in HSC and in the hematopoietic system. Transcriptional analysis of ADM expression in hematopoietic cells from the BLUEPRINT (A), the GSE98791 (B) and the GSE24759 (C) datasets. Scatter plots were generated with the R package ggplot2 (48) (version 3.3.1). Each dot indicates one sample and the bar represents the median value (HSC, hematopoietic stem cells; MPP, hematopoietic multipotent progenitor cells; CMP, common myeloid progenitors; GMP, granulocyte–monocyte progenitors; DC, conventional dendritic cells, CLP, common lymphoid progenitors; NK, natural killer; T reg, regulatory T cells; GC, germinal center; EPC, endothelial progenitor cells; MSC, mesenchymal stem cells; MEP, megakaryocyte-erythroid progenitors; CS, class-switched; TPM, Transcripts Per Million).