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. 2021 May 24;7(6):814–825. doi: 10.1038/s41477-021-00920-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 8 — a, Heat map summarizes the root transcriptomic changes from three independent studies (Supplementary Table 8–12, ①: current study; ②: Harbort and Hashimoto et al., 2020 (ref. ¹³); ③: Teixeira et al., 2021 (ref. ³¹)). The data obtained from pWER::FLS2-GFP plants was shown alongside Col-0 dataset indicating conserved trends of gene expression across different genotypes. DEGs were obtained by pairwise comparisons between live and heat-killed (HK) SynCom treatments (adjusted p-value < 0.05 and fold-change > 1.5). The corresponding data extracted from Harbort and Hashimoto et al., 2020 (ref. ¹³) and Teixeira et al., 2021 (ref. ³¹) were shown on the right. b, Venn diagrams showing the overlapping SynCom-responsive DEGs (live vs. HK SynComs) of each cluster. Most SynCom-responsive DEGs were found in c1, c4, c5, c6 and c8. c, Venn diagram summarizing the overlap of SynCom-responsive DEGs of these independent studies. The core 174 SynCom-responsive host DEGs were highlighted in purple. d, Enrichment of selected GO terms for the 174 core SynCom-responsive DEGs. Numbers in parentheses indicate the total number of DEGs with GO annotations.