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. 2021 Jun 14;23(7):704–717. doi: 10.1016/j.neo.2021.05.006

Table 3.

Univariate survival analysis of RASGRF1 expression in subgroups with different clinical parameters.

PFS OS
Hazard Ratio Hazard Ratio
Clinical parameters n (95%CI) P Value (95%CI) P Value
Age(years)
<65 152 0.339(0.219∼0.524) <0.0001*** 0.361(0.212∼0.616) 0.0015**
≥65 64 0.856(0.417∼1.759) 0.6825 0.809(0.345∼1.897) 0.6372
Gender
Males 118 0.475(0.286∼0.791) 0.0152* 0.419(0.233∼0.755) 0.0185*
Females 98 0.430(0.247∼0.749) 0.0053** 0.550(0.270∼1.120) 0.1189
Type
LUAD 177 0.445(0.299∼0.664) 0.0003*** 0.488(0.295∼0.806) 0.0108*
LUSC 39 0.257(0.081∼0.813) 0.1468 0.331(0.093∼1.174) 0.2486
Clinical stage
I+II 147 0.420(0.253∼0.696) 0.003** 0.385(0.198∼0.748) 0.0174*
III 69 0.572(0.329∼0.997) 0.0743 0.571(0.310∼1.054) 0.1053
T classification
T1 97 0.436(0.237∼0.799) 0.0141* 0.388(0.181∼0.832) 0.033*
T2+T3+T4 119 0.503(0.313∼0.809) 0.0133* 0.549(0.312∼0.966) 0.0679
N classification
N0 136 0.404(0.238∼0.685) 0.0028** 0.402(0.201∼0.867) 0.0264*
N1+N2+N3 80 0.637(0.370∼1.096) 0.1365 0.617(0.336∼1.135) 0.1609
Smoke
No smoking 112 0.427(0.260∼0.704) 0.0019** 0.565(0.294∼1.083) 0.1054
Smoking 104 0.450(0.255∼0.793) 0.022* 0.367(0.195∼0.691) 0.0156*

Note. Bold font indicates P < 0.05.