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. 2021 Jun 14;23(7):704–717. doi: 10.1016/j.neo.2021.05.006

Table 4.

Univariate survival analysis of RASGRF1 expression in subgroups with different clinical parameters.

PFS OS
Hazard Ratio Hazard Ratio
Clinical parameters n (95%CI) P Value (95%CI) P Value
Age(years)
<65 152 2.233(1.426∼3.497) 0.0022** 1.801(1.031∼3.144) 0.0654
≥65 64 3.646(1.908∼6.965) 0.0015** 3.255(1.535∼6.905) 0.0064**
Gender
Males 118 2.118(1.322∼3.396) 0.0038** 1.761(1.019∼3.044) 0.0576
Females 98 5.242(2.884∼9.530) 0.0003*** 6.066(2.803∼13.13) 0.0032**
Type
LUAD 177 3.971(2.589∼6.091) <0.0001*** 4.317(2.477∼7.524) 0.0006***
LUSC 39 1.758(0.695∼4.448) 0.1813 1.764(0.693∼4.492) 0.1859
Clinical stage
I+II 147 3.246(1.957∼5.383) 0.0002*** 2.832(1.466∼5.471) 0.0081**
III 69 1.461(0.821∼2.598) 0.2313 1.086(0.549∼2.149) 0.8144
T classification
T1 97 3.452(1.866∼6.387) 0.0013** 2.641(1.212∼5.757) 0.0407*
T2+T3+T4 119 2.153(1.355∼3.422) 0.0043** 1.781(1.022∼3.104) 0.0632
N classification
N0 136 3.338(1.963∼5.674) 0.0002*** 2.899(1.441∼5.831) 0.0128**
N1+N2+N3 80 1.539(0.893∼2.653) 0.1549 1.288(0.690∼2.405) 0.4303
Smoke
No smoking 112 5.202(3.042∼8.897) <0.0001*** 6.987(3.423∼14.26) 0.0012**
Smoking 104 1.949(1.164∼3.265) 0.0152* 1.602(0.899∼2.855) 0.1255

Note. Bold font indicates P < 0.05.