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. 2021 Mar 26;42(7):1040–1054. doi: 10.1038/s41401-020-00606-z

Fig. 3. Time-lapse video microscopy clip of the shape-dependent phagocytosis of macrophages.

Fig. 3

a The shape-switching PLGA ester ED initially attaches to macrophages without being engulfed. Once the shape changes to a nearly spherical shape, the macrophages rapidly internalize the particles. b Macrophages are scattered on PLGA acid ED, which does not change shape at pH 7.4 but cannot be engulfed completely (Scale bar: 10 μm). With permission from [73].