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. 2021 May 4;46(8):1442–1450. doi: 10.1038/s41386-021-01014-5

Table 3.

Linear mixed effects models testing associations between BOLD activation during response inhibition [StopInh>Go] and subjective reports of sedation.

Estimate SE t p
IFG [50 16 30]
 Order 3.25 1.65 1.98 0.05
 Sex 0.89 0.88 1.02 0.31
 Drinks per week 0.13 0.18 0.73 0.47
Session −1.55 0.52 2.99 <0.01
 IFG activation (ß weights) 1.60 1.37 1.17 0.25
 Beverage −0.67 1.01 0.67 0.51
 Time (Linear) 2.10 0.51 4.14 <0.01
 Time 2 (Quadratic) −0.36 0.09 3.87 <0.01
 Session × Time −0.56 0.49 1.14 0.25
 Session × Time2 0.13 0.09 1.39 0.17
 Session × Beverage −0.17 0.74 0.24 0.81
 IFG activation × Session 0.02 0.68 0.03 0.98
 IFG activation × Beverage −1.30 1.34 0.97 0.33
 IFG activation × Time −1.90 0.67 2.85 <0.01
 IFG activation × Time 2 0.34 0.12 2.76 <0.01
 Beverage × Time 1.84 0.69 2.67 0.01
 Beverage × Time 2 −0.15 0.13 1.10 0.27
 Session × Beverage × Time 0.84 0.69 1.21 0.23
 Session × Beverage × Time2 −0.14 0.13 1.02 0.31
 Session × Beverage × IFG activation 0.39 0.97 0.41 0.69
 Session × IFG activation × Time 0.88 0.64 1.36 0.17
 Session × IFG activation × Time2 −0.13 0.12 1.08 0.28
 IFG activation × Beverage × Time 2.51 0.91 2.75 0.01
 IFG activation × Beverage × Time 2 −0.49 0.18 2.78 0.01
 IFG activation × Beverage × Time × Session −1.42 0.91 1.56 0.12
 IFG activation × Beverage ×Time× Session 0.22 0.18 1.24 0.21

IFG (inferior frontal gyrus) activation = the extracted BOLD signal (ß weights, from a 10mm-radius sphere surrounding significant peak voxel [50 16 30]) from the StopInh>Go contrast.