Table 2.

Neuropsychological domain-specific effects between impaired and spared cluster and healthy controls in discovery and validation sample.

	Overall			Impaired vs. spared		Impaired vs. HC		Spared vs. HC
	T (max)	p (uncorr)	p (FDR)	p (FDR)	Cohen’s d	p (FDR)	Cohen’s d	p (FDR)	Cohen’s d
Discovery
Social cognition	0.980	0.583	0.583	–	–	–	–	–	–
Working memory	6.089	<0.001	<0.001***	0.004**	0.68	<0.001***	1.11	0.053	0.28
Processing speed	10.070	<0.001	<0.001***	<0.001***	1.90	<0.001***	2.12	0.223	−0.17
Executive functioning	5.416	<0.001	<0.001***	<0.001***	−1.62	<0.001***	−0.78	<0.001***	0.53
Attention	8.756	<0.001	<0.001***	<0.001***	1.02	<0.001***	2.05	<0.001***	0.65
Verbal memory	10.385	<0.001	<0.001***	<0.001***	−1.39	<0.001***	−2.44	0.001**	−0.48
Visual memory	8.423	<0.001	<0.001***	<0.001***	1.45	<0.001***	1.67	0.003**	−0.44
Salience	2.646	0.022	0.023*	0.175	−0.28	0.913	−0.02	0.003**	0.45
Validation
Social_cognition	2.824	0.012	0.014*	0.008**	−1.13	0.010*	−0.75	0.159	–
Working_memory	0.792	0.700	0.720	–	–	–	–	–	–
Processing_speed	7.256	<0.001	<0.001***	<0.001***	1.91	<0.001***	2.48	0.007**	0.50
Executive_functioning	2.497	0.031	0.034*	0.020*	0.98	0.023*	0.67	0.212	–
Attention	0.249	0.965	0.965	–	–	–	–	–	–
Verbal_memory	7.112	<0.001	<0.001***	<0.001***	−1.48	<0.001***	−2.51	0.050	–
Visual_memory	8.628	<0.001	<0.001***	<0.001***	2.29	<0.001***	3.04	0.052	–
Salience	3.533	0.001	0.001**	0.008**	−1.12	<0.001***	−1.03	0.578	–

HC healthy control.

*p < 0.05, **p < 0.01, ***p < 0.001.