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Site of CNS relapse by CNS prophylaxis.
| Site of CNS relapse | |||
|---|---|---|---|
| CNS prophylaxis regimen | Leptomeninges | Parenchyma | Both |
| IT | 5 (42%) | 3 (25%) | 4 (33%) |
| HD-MTX | 1 (50%) | 1 (50%) | – |
| No prophylaxis | 5 (23%) | 13 (57%) | 4 (18%) |
CNS central nervous system, IT intrathecal, MTX methotrexate, HD high-dose.
