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. 2021 Jun 16;11:12703. doi: 10.1038/s41598-021-92220-0

Table 2.

Main documented bacterial coinfections according to the type of viral disease.

Variable Influenza (N = 63) SARS-CoV-2 (N = 81) p-value
Gram positive-early 15 (24%) 11 (14%) 0.2
Gram positive-late 6 (9.5%) 23 (28%) 0.010
Gram positive-total 21 (33%) 34 (42%) 0.4
Gram negative-early 26 (41%) 20 (25%) 0.053
Gram negative-late 21 (33%) 41 (51%) 0.056
Gram negative-total 47 (75%) 61 (75%)  > 0.9
Pseud. aeruginosa-early 11 (17%) 9 (11%) 0.4
Pseud. aeruginosa-late 9 (14%) 11 (14%)  > 0.9
Pseud. aeruginosa-total 20 (32%) 20 (25%) 0.5
E. coli-early 6 (9.5%) 7 (8.6%)  > 0.9
E. coli-late 4 (6.3%) 7 (8.6%) 0.8
E. coli-total 10 (16%) 14 (17%)  > 0.9
Enterobacter-early 1 (1.6%) 0 (0%) 0.4
Enterobacter-late 0 (0%) 5 (6.2%) 0.068
Enterobacter-total 1 (1.6%) 5 (6.2%) 0.2
Acinetobacter-early 2 (3.2%) 1 (1.2%) 0.6
Acinetobacter-late 6 (9.5%) 11 (14%) 0.6
Acinetobacter-total 8 (13%) 12 (15%)  > 0.9
Staph. aureus-early 7 (11%) 6 (7.4%) 0.6
Staph. aureus-late 4 (6.3%) 12 (15%) 0.2
Staph. aureus-total 11 (17%) 18 (22%) 0.6
Proteus mirabilis-early 0 (0%) 2 (2.5%) 0.5
Proteus mirabilis-late 0 (0%) 2 (2.5%) 0.5
Proteus mirabilis-total 0 (0%) 4 (4.9%) 0.13
Enterococcus-early 0 (0%) 2 (2.5%) 0.5
Enterococcus-late 0 (0%) 5 (6.2%) 0.068
Enterococcus-total 0 (0%) 7 (8.6%) 0.018
Coryneb. striatum-early 4 (6.3%) 1 (1.2%) 0.2
Coryneb. striatum-late 0 (0%) 6 (7.4%) 0.035
Coryneb. striatum-total 4 (6.3%) 7 (8.6%) 0.8
K. Pneumoniae-early 2 (3.2%) 3 (3.7%)  > 0.9
K. Pneumoniae-late 0 (0%) 7 (8.6%) 0.018
K. Pneumoniae-total 2 (3.2%) 10 (12%) 0.095
S. marcescens-early 1 (1.6%) 0 (0%) 0.4
S. marcescens-late 0 (0%) 4 (4.9%) 0.13
S. marcescens-total 1 (1.6%) 4 (4.9%) 0.4
Strep. Pneumonia-early 5 (7.9%) 2 (2.5%) 0.2
Strep. Pneumonia-late 2 (3.2%) 1 (1.2%) 0.6
Strep. Pneumonia-total 7 (11%) 3 (3.7%) 0.10
H. influenza-early 5 (7.9%) 2 (2.5%) 0.2
H. influenza-late 2 (3.2%) 5 (6.2%) 0.5
H. influenza-total 7 (11%) 7 (8.6%) 0.8
Stenotr. Maltophilia-early 1 (1.6%) 0 (0%) 0.4
Stenotr. Maltophilia-late 3 (4.8%) 6 (7.4%) 0.7
Stenotr. Maltophilia-total 4 (6.3%) 6 (7.4%)  > 0.9
Actinomyces-early 1 (1.6%) 1 (1.2%)  > 0.9
Actinomyces-late 1 (1.6%) 2 (2.5%)  > 0.9
Actinomyces-total 2 (3.2%) 3 (3.7%)  > 0.9
Other-early 1 (1.6%) 1 (1.2%)  > 0.9
Other-late 1 (1.6%) 2 (2.5%)  > 0.9
Other-total 2 (3.2%) 3 (3.7%)  > 0.9
Hospitalization length 8 (4, 21) 12 (6, 23) 0.10
Days to first bacteria 1.0 (1.0, 3.0) 4.0 (1.0, 8.0)  < 0.001