Table 3.

Univariate analysis of variables associated with death.

	Influenza (n = 724)			COVID-19 (n = 642)
	OR (95% CI)		p-value	OR (95% CI)		p-value
Bacteria growth (time)
Early < 48 h	3.09 (1.11–7.38)		0.018	2.70 (1.22–5.83)		0.012
Late > 48 h	4.78 (1.67–12)		0.002	7.00 (3.88–13.0)		< 0.001
Coinfection count	2.08 (1.3–3.21)		0.001	2.52 (1.86–3.54)		< 0.001
Number of coinfections
1	3.42 (1.47–7.26)		0.002	3.33 (1.86–5.96)		< 0.001
> 1	5.32 (1.15–18.7)		0.015	11.3 (4.95–29.2)		< 0.001
Hospitalization lengthdays	1.04 (1.02–1.06)		< 0.001	1.02 (1.01–1.04)		0.003
Gender (male)	1.29 (0.73–2.30)		0.4	1.31 (0.91–1.89)		0.15
Age	1.00 (0.99–1.01)		0.6	1.01 (1.00–1.02)		0.013
Body mass index (BMI)	1.00 (1.00–1.00)		> 0.9	1.00 (1.00–1.00)		0.7
Systolic blood pressuremin	0.93 (0.92–0.95)		< 0.001	0.95 (0.94–0.96)		< 0.001
Blood oxygen saturationmin	0.88 (0.84–0.91)		< 0.001	0.87 (0.85–0.90)		< 0.001
Fevermax	1.74 (1.26–2.44)		< 0.001	1.48 (1.22–1.82)		< 0.001
Albuminmin	0.13 (0.08–0.21)		< 0.001	0.12 (0.08–0.17)		< 0.001
Lymphocytesmin	0.15 (0.05–0.37)		< 0.001	0.15 (0.09–0.26)		< 0.001
International normalized ratiomax	1.34 (0.94–1.85)		0.071	3.83 (2.34–6.65)		< 0.001
C-Reactive proteinmax	1.07 (1.05–1.1)		< 0.001	1.09 (1.07–1.11)		< 0.001
Total Bilirubinmax	1.58 (1.29–2)		< 0.001	1.61 (1.37–1.93)		< 0.001
White blood cellsmax	1.05 (1.02–1.09)		0.010	1.12 (1.09–1.15)		< 0.001
Neutrophilsmax	1.12 (1.07–1.17)		< 0.001	1.15 (1.12–1.18)		< 0.001
Ferritinmax	1.00 (1.00–1.00)		0.026	1.00 (1.00–1.00)		< 0.001
Lactate dehydrogenasemax	1.00 (1.00–1.00)		< 0.001	1.00 (1.00–1.00)		< 0.001
Number of coinfections (first 48 h)	1.92 (0.96–3.44)		0.037	1.84 (1.11–3.22)		0.022
Number of coinfections (2–14 days)	3.20 (1.45–6.59)		0.002	2.91(2.00- 4.46)		< 0.001
Days to First bacteria growth	1.00 (0.90–1.10)		> 0.9	0.97 (0.93–1.02)		0.3

OR, odds ratio; CI, confidence interval; min, minimal levels; max, maximal levels.