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. 2020 Aug 18;42(7):1124–1138. doi: 10.1038/s41401-020-0497-0

Fig. 2. BAH attenuates clinical severity, fibrosis and inflammatory-related biomarkers in the TNBS model.

Fig. 2

a BAH significantly ameliorated the decrease in body weight induced by TNBS. Significance was determined by two-way ANOVA followed by Tukey’s post hoc test. b Colon length was measured at the time of sacrifice and was compared between groups. Significance was determined by one-way ANOVA followed by Dunnett’s post hoc test. Panel c depicts histological sections stained with H&E or picrosirius red/fast green as well as images from immunohistochemistry experiments performed on macrophages (F4/80) or lymphocyte T (CD3) and from TNC immunofluorescence. Representative images are shown at the indicated magnification. d Quantification of different markers from panel c. All results are shown as the mean ± SEM (n = 4–10 animals per group), and significance was determined by one-way ANOVA followed by Tukey’s post hoc test, with the exception of the histological score (Dunnett’s test). **P < 0.01 and ***P < 0.001 for TNBS + vehicle vs control + vehicle; #P < 0.05, ##P < 0.01, and ###P < 0.001 for TNBS + BAH vs TNBS + vehicle.