Table 2.
Incidence of heart failure and ventricular arrhythmia composite in people with PVC.
| n | Event number |
Follow-up duration (person * years) |
Incidence | Model 1 | Model 2 | Model 3 | Model 4 | |
|---|---|---|---|---|---|---|---|---|
| Heart failure | ||||||||
| No PVC | 9,739,067 | 154,493 | 89,450,468 | 1.727 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
| All PVC (PVC 1 + PVC 2) | 4515 | 165 | 40,899 | 4.034 | 2.344 (2.013–2.729) | 1.439 (1.235–1.676) | 1.46 (1.253–1.701) | 1.371 (1.177–1.598) |
| PVC 1 | 2334 | 79 | 21,278 | 3.713 | 2.150 (1.724–2.679) | 1.421 (1.140–1.772) | 1.459 (1.170–1.819) | 1.434 (1.150–1.788) |
| PVC 2 | 2181 | 86 | 19,621 | 4.383 | 2.563 (2.077–3.163) | 1.455 (1.178–1.797) | 1.461 (1.183–1.805) | 1.319 (1.067–1.629) |
| Ventricular arrhythmia composite | ||||||||
| No PVC | 9,739,067 | 25,291 | 89,718,315 | 0.282 | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
| All PVC (PVC 1 + PVC 2) | 4515 | 92 | 40,922 | 2.248 | 7.967 (6.492–9.777) | 5.952 (4.852–7.303) | 5.932 (4.833–7.280) | 5.588 (4.553–6.859) |
| PVC 1 | 2334 | 28 | 21,337 | 1.312 | 4.665 (3.222–6.754) | 3.656 (2.524–5.296) | 3.659 (2.526–5.301) | 3.573 (2.467–5.176) |
| PVC 2 | 2181 | 64 | 19,585 | 3.268 | 11.616 (9.092–14.839) | 8.162 (6.387–10.432) | 8.145 (6.373–10.41) | 7.420 (5.805–9.484) |
Incidence is per 1000 person * years.
Model 1 is without multivariate adjustment.
Model 2 is adjusted for age and sex.
Model 3 is adjusted for age, sex, BMI, smoking status, alcohol consumption, and physical activity.
Model 4 is adjusted for age, sex, BMI, smoking status, alcohol consumption, physical activity, hypertension, diabetes, and dyslipidemia.
AF atrial fibrillation, PVC premature ventricular contraction.