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. 2021 Mar 23;42(7):1069–1079. doi: 10.1038/s41401-021-00634-3

Fig. 1. Artemisinin improved cognitive impairment in an LPS-induced sepsis model.

Fig. 1

a Timeline of the in vivo experimental treatments. b Murine sepsis score (MSS) at different time points. c Neurobehavioral score at different time point. d The expression levels of IL-6 and TNF-α in the serum and brain were measured by ELISA. e Analysis of the data obtained in the Morris water maze test. The escape latency was recorded in the positioning navigation experiment. The average swimming speed, swimming distance, and percentage of total time in the target quadrant were recorded in the space exploration experiment. f The percentage of alternations was observed in the Y maze spontaneous alternation test. *P < 0.05 versus sham group mice. #P < 0.05 versus LPS-treated mice. n = 6.