Table 1.
Participant’s characteristics.
| ID | Age | Sex | Race | Education | Arm Trained | Mesulam | Baseline ARAT | ARATpost | ΔARAT | Lesion Volume (mm3) | Lesion Location | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 03 | 60 | F | Afr. Amer. | NA | Dom | 1 | 39 | 57 | 18 | 2452 | L CR & BG / R BG |
| 2 | 22 | 54 | M | Afr. Amer. | HS | Dom | 1 | 41 | 57 | 16 | 29,178 | Bil Cerebellar Hemisphere (R > L) |
| 3 | 34 | 53 | F | Caucasian | < College | Dom | 0 | 40 | 55 | 15 | NA | Not identifiable |
| 4 | 01 | 37 | M | Afr. Amer. | HS | Dom | 15 | 27 | 40 | 13 | 48,240 | L Frontal/Parietal/Insula/Occipital (C + S); L thalamic & BG lacune / Bilateral cerebellar lacune |
| 5 | 24 | 82 | M | Caucasian | NA | Dom | 0 | 16 | 27 | 11 | 90,095 | L Frontal/Parietal/Temporal/Insula (C + S); L CR and BG |
| 6 | 44 | 48 | F | Afr. Amer. | < College | Dom | 2 | 40 | 49 | 9 | 482 | L CR, Thalamus, BG, genu of the internal capsule;R PLIC lacune |
| 7 | 02 | 60 | F | Caucasian | < College | Dom | 0 | 31 | 40 | 9 | 35,646 | L Frontal/Parietal (C + S); L Insula (C) |
| 8 | 19 | 61 | M | Afr. Amer. | HS | Dom | 0 | 39 | 47 | 8 | 5124 | L Frontal (S), CC, CR, BG, thalamus, ALIC, L middle cerebellar peduncle / R VA thalamus lacune; pons |
| 9 | 38 | 59 | F | Caucasian | < College | Dom | 1 | 48 | 55 | 7 | 61 | L genu of the internal capsule |
| 10 | 08 | 60 | M | Afr. Amer. | < College | Non-Dom | 3 | 39 | 46 | 7 | 434 | R CR & BG / L CR & cerebellum |
| 11 | 43 | 56 | M | Caucasian | HS | Non-Dom | 1 | 37 | 44 | 7 | 13,118 | R parietal/posterior insula (C + S) |
| 12 | 35 | 65 | M | Afr. Amer. | < College | Dom | 26 | 32 | 38 | 6 | 1562 | L prefrontal (S), multiple bilateral thalamic and BG lacunes and L pons |
| 13 | 12 | 58 | M | Afr. Amer. | HS | Dom | 0 | 30 | 36 | 6 | 463 | L Frontal/Parietal (C + S) / R Frontal/Temporal (C + S) |
| 14 | 41 | 54 | M | Caucasian | HS | Non-Dom | 2 | 38 | 43 | 5 | 72,119 | R Frontal/Parietal/Temporal/Insula (C + S), thalamus, and basal ganglia |
| 15 | 18 | 70 | M | Afr. Amer. | HS | Dom | 5 | 37 | 42 | 5 | 7108 | L frontal (S), CR, PLIC, thalamus, and BG |
| 16 | 30 | 56 | M | Caucasian | < College | Dom | 0 | 25 | 30 | 5 | 134 | L PLIC |
| 17 | 33 | 50 | M | Caucasian | HS | Dom | 0 | 38 | 42 | 4 | 7209 | L CR, BG, subinsula |
| 18 | 27 | 42 | F | Caucasian | HS | Non-Dom | 2 | 33 | 37 | 4 | 12,757 | R CR, BG, insula (C + S), medial temporal lobe |
| 19 | 40 | 79 | NA | NA | < College | Dom | 2 | 31 | 35 | 4 | NA | Not identifiable lesion |
| 20 | 17 | 77 | F | Afr. Amer. | NA | Dom | 12 | 10 | 14 | 4 | 386 | L pontine / R BG and thalamic lacune |
| 21 | 10 | 52 | M | Afr. Amer. | HS | Non-Dom | 0 | 13 | 15 | 2 | 12,631 | R frontal (S) CR & BG, superior occipital frontal fasciculus / L cerebellar lacune / L thalamic lacune |
| 22 | 13 | 60 | F | Afr. Amer. | HS | Non-Dom | 0 | 10 | 12 | 2 | 981 | R CR & BG |
| 23 | 37 | 66 | F | Afr. Amer. | < College | Non-Dom | 0 | 38 | 39 | 1 | 884 | R thalamus |
| 24 | 26 | 60 | M | Caucasian | < College | Non-Dom | 1 | 38 | 39 | 1 | 413 | L Thalamus / PLIC |
| 25 | 20 | 53 | F | Afr. Amer. | NA | Dom | 3 | 37 | 38 | 1 | NA | Not identifiable lesion |
| 26 | 23 | 66 | F | Caucasian | VS/TS | Dom | 1 | 36 | 37 | 1 | 910 | L thalamus & BG lacune, cerebral peduncle |
| 27 | 21 | 54 | M | Caucasian | < College | Non-Dom | 8 | 39 | 39 | 0 | NA | Not identifiable lesion |
| 28 | 45 | 79 | M | Caucasian | NA | Non-Dom | 6 | 17 | 17 | 0 | 791 | L insular cortex (S), CR |
| 29 | 09 | 64 | F | Afr. Amer. | HS | Dom | 5 | 33 | 31 | −2 | 38,940 | L parietal/temporal/occipital (C + S), cerebellum, thalamus-pulvinar, and PLIC / R internal capsule |
| 30 | 11 | 61 | M | Caucasian | < College | Non-Dom | 0 | 32 | 29 | −3 | 233 | L pontomedulary junction / inferior cerebellar peduncle |
| Summary Mean ± SD | 59.87 ± 10.36 | 17 M, 12F, 1NA | 15 Afr. American 14 Caucasian 1NA | 12 HS 1 VS/TS 12 < College 5NA | 21 Dom, 9 Non-Dom | 3.23 ± 5.63 | 32.13 ± 9.80 | 37.67 ± 11.86 | 5.53 ± 5.20 | 14705.81 ± 23449.36 | 18 (S), 8 (C + S), 4NA | |
Legend: Afr. Amer. = African American, Dom = Dominant, Non-Dom: Non-Dominant, IM = Individualized Maximum, HS = High School, VS/TS = Vocational School / Technical School. R = Right, L = Left, MCA = Middle Cerebral Artery, PCA = Posterior Cerebral Artery, PLIC = Posterior Limb of the Internal Capsule.
C = cortical, S = subcortical, CR = corona radiata, BG = basal ganglia, ALIC = anterior limb of the internal capsule, PLIC = posterior limb of the internal capsule, VA = ventral anterior nucleus.