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. 2020 Jan 10;8(4):569–579. doi: 10.1016/j.gendis.2020.01.004

Figure 6.

Figure 6

EGCG alleviates cTnIR193H induced PDE4D low expression. Primary neonatal cardiomyocytes overexpressing cTnIR193H with or without EGCG treatment were used for these experiments. (A) PDE4D protein level in NC group, cTnIR193H group and cTnIR193H + EGCG group. (B) ChiP assays for detecting the enrichment of cTnIR193H and HDAC1 with or without EGCG treatment. (C) ChiP assays for detecting the enrichment of acH3K4 and acH3K9 with or without EGCG treatment. The results are expressed as mean ± SD. Statistical significance was determined by ANOVA followed by LSD tests. *P < 0.05; n = 6 per group.