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. 2021 Jun 3;12:675778. doi: 10.3389/fphys.2021.675778

TABLE 5.

Papillary muscle function after changes in extracellular calcium concentration.

Groups 0.625 mM 1.25 mM 2.5 Mm
DT (g/mm2) W 3.36 ± 0.82 5.27 ± 0.98 6.13 ± 1.38
W-EX 3.34 ± 0.77 5.14 ± 0.83 5.88 ± 1.10
SHR 4.40 ± 1.27* 6.15 ± 1.55* 6.58 ± 1.33
SHR-EX 5.16 ± 0.97 6.62 ± 1.26# 6.87 ± 1.33#
RT (g/mm2) W 0.49 ± 0.14 0.49 ± 0.14 0.49 ± 0.13
W-EX 0.46 ± 0.10 0.45 ± 0.09 0.47 ± 0.09
SHR 0.71 ± 0.15* 0.70 ± 0.16* 0.72 ± 0.19*
SHR-EX 0.74 ± 0.23# 0.75 ± 0.23# 0.80 ± 0.25#
+dT/dt (g/mm2/s) W 35.0 ± 9.12 56.7 ± 12.5 69.3 ± 16.9
W-EX 35.2 ± 6.42 55.7 ± 8.69 66.2 ± 14.1
SHR 38.5 ± 10.4 58.5 ± 16.7 63.8 ± 14.6
SHR-EX 48.8 ± 9.53 66.5 ± 12.7 71.9 ± 15.2
-dT/dt (g/mm2/s) W 15.8 ± 3.50 22.2 ± 3.61 23.4 ± 4.68
W-EX 15.1 ± 2.26 21.6 ± 2.42 22.7 ± 3.43
SHR 20.0 ± 5.40* 25.5 ± 5.29* 26.0 ± 4.22
SHR-EX 22.4 ± 3.45# 26.2 ± 3.99# 26.4 ± 4.05#

Data as mean ± standard deviation. W, Wistar rats; W-EX, exercised Wistar rats; SHR, spontaneously hypertensive rats; SHR-EX, exercised SHR; DT, developed tension; RT, resting tension; +dT/dt, maximum rate of tension development; –dT/dt, maximum rate of tension decrease. ANOVA for a 2 × 2 factorial design and Tukey; *p < 0.05 vs. W; #p < 0.05 vs W-EX; §p < 0.05 vs. SHR.