TABLE 7.
Oxidative stress and energy metabolism.
| W (n = 8) | W-EX (n = 8) | SHR (n = 8) | SHR-EX (n = 8) | |
| Serum MDA (μM/L) | 1.83 ± 0.39 | 1.74 ± 0.37 | 1.86 ± 0.42 | 2.01 ± 0.74 |
| Myocardial MDA (nmol/mg protein | 0.86 ± 0.12 | 0.70 ± 0.06 | 0.87 ± 0.22 | 0.76 ± 0.25 |
| Lip. Hydrop. (nmol/g tissue) | 203 ± 33 | 183 ± 26 | 248 ± 24* | 226 ± 38# |
| NADPH oxidase activity (x106 UA/mg protein) | 3.42 ± 1.4 | 2.65 ± 1.45 | 2.50 ± 0.98 | 2.87 ± 0.70 |
| Citrate synthase (nmoL/mg protein) | 23.8 ± 4.26 | 26.9 ± 4.96 | 19.8 ± 3.24 | 30.0 ± 6.14§ |
| β-HAD (nmoL/mg protein) | 38.5 ± 7.20 | 36.4 ± 8.36 | 25.7 ± 5.68* | 36.8 ± 7.52§ |
| Lactate dehydrogenase (nmol/mg protein) | 89.5 ± 8.79 | 81.2 ± 11.2 | 123 ± 18.7* | 89.2 ± 13.6§ |
Data as mean ± standard deviation. W, Wistar rats; W-EX, exercised Wistar rats; SHR, spontaneously hypertensive rats; SHR-EX, exercised SHR; MDA, malondialdehyde concentration; Lip. hydrop., lipid hydroperoxide concentration; β-HAD, β-hydroxyacyl dehydrogenase. ANOVA for a 2 × 2 factorial design and Tukey; *p < 0.05 vs. W; #p < 0.05 vs. W-EX; §p < 0.05 vs. SHR.