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. 2021 Jun 3;11:683951. doi: 10.3389/fonc.2021.683951

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Copyright © 2021 Du, Miao, Jiang, Cao, Wang, Wang, Yu, Wang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of CALU with subgroup survival and clinical characteristics. (A) the expression level of CALU altered the OS of BLCA patients in multiple subgroups, including male (p=0.012), female (p=0.014), high grade (p=0.002), Stage I-II (p=0.026), Stage III-IV (p=0.031), T1-T2 (p=0.013), N0-N1 (p=0.002) and M0 (p=0.006). (B) Tumor tissue with higher grade (p<0.001), stage(p<0.001), T (p=0.003), N (p<0.001),M (p=0.024) classification expressed higher CALU. ****p<0.0001, ***p<0.001, **p<0.01, *p<0.05. NS, not significant.